Primary Antibody Matched Pairs
Medchemexpress LLC CANT1 Human HEK293 50ug
CANT1 is a calcium-dependent nucleotidase that shows a clear preference for UDP and the order of its enzymatic activity is UDP GDP UTP GTP It is worth noting that it has little activity on ADP and even less activity on ATP but it does not hydrolyze AMP and GMP CANT1 Protein Human (HEK293 His) is the recombinant human-derived CANT1 protein expressed by HEK293 with N-His labeled tag
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker)(PRF1/2467), CF568 conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjug
Meso Scale Discovery SPLEX HUM IL13 KitQP 25 PL
The Meso Scale Discovery S-PLEX Human IL-13 Kit is a multiplex immunoassay for measuring IL-13 in human serum plasma and cell culture supernatant It uses electrochemiluminescence detection offering high sensitivity a wide dynamic range and low sample volume needs The kit includes a 96-well plate with capture antibodies ruthenium-labeled detection antibodies buffers diluent and calibrators The assay takes 3 5 hours and requires a MESO QuickPlex SQ 120 instrument It quantifies IL-13 important in immune responses
ABclonal Technology GIT2 Rabbit pAb
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.
Biotium CD79b (B-Cell Marker)(IGB/2940R), CF647 conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Medchemexpress LLC Cellular retinoic acid-binding protein 2 (CRABP2) | 100 UG
Recombinant human cellular retinoic acid-binding protein 2 (CRABP2), expressed in E. coli and supplied as a His-tagged, lyophilized protein. Supplied as a 100 μg vial in lyophilized powder form, formulated from Tris-HCl and NaCl. Suitable for in vitro biochemical and cell biology studies of retinoic acid binding and signaling.
American Research Products Inc PrEST Antigen PIH1D1
PrEST Antigen PIH1D1 antigen APrEST82495 for PIH1 domain containing 1 Recombinant protein fragment of Human PIH1D1
Biotium Cathepsin D (Tumor Marker)(CTSD/3276), CF568 conjugate, 0.1mg/mL
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blu
ABclonal Technology GSTO1 Rabbit pAb
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(CPTC-ANXA1-1), CF740 conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluo
ABclonal Technology TRIM72 Rabbit pAb
Enables identical protein binding activity. Predicted to be involved in several processes, including cellular protein metabolic process, plasma membrane repair, and protein homooligomerization. Predicted to act upstream of or within negative regulation of insulin receptor signaling pathway, negative regulation of insulin-like growth factor receptor signaling pathway, and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma.
Human IL5 MAb 20ul (Sino Biological)
This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-5/IL5 / Interleukin 5 (rh IL-5/IL5 / Interleukin 5; Catalog#15673-HNCE; P05113; Ile20-Ser134).
Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(5E4/1), Biotin conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluo
ABclonal Technology TRIM25 Rabbit pAb
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is an RNA binding protein, functions as a ubiquitin E3 ligase and is involved in multiple cellular processes, including regulation of antiviral innate immunity.
Sino Biological Protein Human IL6R IL6 1MG
A DNA sequence encoding the Human IL-6/IL-6R alpha Chimera (P08887 & P05231) (Leu20-Asp358 & Val30-Met212) was expressed, with a polyhistidine tag at the N-terminus.